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It's another great weekend to be in Philadelphia, with the kick-off of Philly Beer Week 2012, the annual Bike Race, the newly expanded two-day Roots Picnic on Penn's Landing and First Friday in more neighborhoods than ever before. (Photo credits, clockwise from top left: G. Widman for GPTMC, R. Kennedy for GPTMC, K. Ciappa for GPTMC, M. Kennedy for GPTMC)

Philadelphia rings in the first weekend of June with happenings aplenty, from the epic 2012 Roots Picnic, expanded to two days for the first time, to First Friday across a hefty handful of neighborhoods across the region.

It’s going to be excellent weather for restaurant- and bar-hopping around the city, and luckily a few great new watering holes have opened up to help you do just that.

Plus, be sure to follow uwishunu on Twitter all weekend long to keep up-to-date on everything going down all weekend long. No need for a personal schedule or itinerary; you just need our Twitter feed.

Our top picks for your best weekend, below:

Friday, June 1

First Friday in Manayunk, Kennett Square, Old City, Doylestown, Northern Liberties, on Frankford Avenue and Chestnut Hill

Opening Tap on Independence Mall **Philly Beer Week

First Friday at the Barnes Foundation

Friday Night unWINEd at Shadybrook Farm

APIARY 4 Launch Party and Late-Night Literary Carnival

Tangle Arts Presents “Half-life”: Circus-Theater Meets Science Fiction (Fri, Sat)

SALSA CALIENTE BYOB Cabaret and Dance Party at the Painted Bride Art Center

June First Friday at Arden Theatre Company

Philadelphia Live Arts Festival & Philly Fringe JumpStart (Fri, Sat)

5th Annual NarBark Dog Parade

InterAct Theatre Company’s Etched In Skin On A Sunlit Night — Opening Day!

Rittenhouse Square Fine Art Show (Fri, Sat, Sun)

Transit of Venus Celebration at American Philosophical Society and Franklin Institute

Philly MFA Pop-Up

Valanni’s “Gay Beer Week” (Fri, Sat, Sun) — Opening Day! **Philly Beer Week

Martinis On The Portico at the Philadelphia Museum of Art

Arden Theatre’s Robin Hood (Fri, Sat, Sun)

Bistrot La Minette Movie Under the Stars

Lantern Theater Company’s The Island (Fri, Sat, Sun)

Saturday, June 2

The 2012 Roots Picnic at Penn’s Landing (Sat, Sun)

18th Street Outdoor Cafe in conjunction with the Rittenhouse Square Fine Art Show

2012 USA Sevens Collegiate Rugby Championship at PPL Park (Fri, Sat)

Fourth Annual Great Beer Expo at the Navy Yard **Philly Beer Week

Drexel’s annual student fashion show

The Bailey Hounds: BYOB Gothic Americana Blues & Folk-Inspired Music Concert at Laurel Hill

Rock to the Future’s Rockin’ Rummage Sale at First Unitarian Church

Ride The Rails with Boxcar Brewing Company **Philly Beer Week

Philadelphia Theatre Company’s Reasons To Be Pretty (Fri, Sat, Sun)

More Weekend Picks, below.

Maya.2012: Lords of Time at the Penn Museum (Fri, Sat, Sun)

Morris Arboretum’s Garden Railway (Fri, Sat, Sun)

“Free at the Kimmel” Series

Act II Playhouse’s My Fair Lady (Fri, Sat, Sun)

PAFA and Dr. Barnes (Fri, Sat, Sun)

Paddle Penn’s Landing (Sat, Sun)

Salvatore Pinto: A Retrospective Celebrating the Barnes Legacy at the Woodmere Art Museum (Fri, Sat, Sun)

The Walnut Street Theatre’s The Buddy Holly Story (Fri, Sat, Sun)

Materials Transformed: The Art of African Sculpture at the Free Library of Philadelphia (Fri, Sat, Sun)

Craft Spoken Here at the Philadelphia Museum of Art (Fri, Sat, Sun)

Dead Sea Scrolls: Life and Faith in Ancient Times at the Franklin Institute (Fri, Sat, Sun)

Sunday, June 3

The Philadelphia International Bike Race

116th Annual Devon Horse Show (Fri, Sat, Sun) — Closing Day!

Indoor Italian Street Fair at The Farmers’ Cabinet **Philly Beer Week

Second Annual Big Ass Iron Hill Beer Dinner at Good Dog **Philly Beer Week

Fairmount Restaurant Week — Closing Day!

PA Ballet’s N.Y. Export: Opus Jazz (Fri, Sat, Sun) — Closing Day!

Craft Beer Day on East Passyunk Avenue **Philly Beer Week

Free First Sunday at The Barnes

Italian National Day Festival on East Passyunk Avenue

Morgan’s Pier Sundae Summer Open Air Dance Party

Arden Theatre’s Tulipomania (Fri, Sat, Sun)

“Run! The Super-Athletes of the Sierra Madre” at the Penn Museum (Fri, Sat, Sun)

From Asbury Park to the Promised Land: The Life and Music of Bruce Springsteen at the National Constitution Center (Fri, Sat, Sun)

On My Honor: 100 Years of Girl Scouting at the National Constitution Center (Fri, Sat, Sun)

Alert Today, Alive Tomorrow: Living with the Atomic Bomb, 1945-1965 at the Mercer Museum (Fri, Sat, Sun)

Offering Of The Angels: Treasures From The Uffizi at the Michener Art Museum (Fri, Sat, Sun)